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Type 2 diabetes mellitus: A risk factor for Helicobacter pylori infection: A hospital based case- control study


Objective: To determine the frequency of Helicobacter pylori (H. pylori) infection in diabetic and non-diabetic patients and to compare the frequency of H. pylori infection in both groups. Study Design: Case control.
Place and Duration: Department of Medicine, Liaquat University Hospital from October 2007 to March 2008.
Materials and Methods: This hospital-based casecontrol study was conducted on 148 subjects and divided into two groups i.e. type 2 diabetics and non-diabetics; each group consisting of 74 patients. All diabetic patients of 35 years of age, both gender and the known cases with history of dyspepsia, epigastric pain or bloating for more than a month were screened for Helicobacter pylori infection. The collected data of both groups was evaluated and separated for analysis.
Results: Majorityof the patients were male with mean age  SD, 52.86 8.51. Among the diabetic group, HpSA was positive in 54/74 (73%), whereas in the non-diabetic group HpSA was positive in 38/74 (51.4%) cases. Fasting blood glucose was identifi ed as low in 04 (5.40%) H. pylori infected - diabetic patients where as the blood glucose level of 07 (9.45%) known diabetic patients was raised despite the ongoing medication.

Bekha Ram Devrajani, Syed Zulfiquar Ali Shah, Aftab Ahmed Soomro, Tarachand Devrajani

Publishing Source:
Volume 30, Issue 1, Jan - Mar 2010


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